Evolution of Epigenome as the Blueprint for Carcinogenesis

Epigenetics “above or over genetics” is the term used for processes that result in modifications which are stably inherited through cell generations, without changing underlying DNA sequence of cell. These include methylation, Post-translational histone modification and non-coding RNAs. Over last two decades, interest field epigenetics has grown manifold because realization its involvement key cellular pathological beyond what was initially anticipated. chromatin biology have been underscored to play roles diseases like cancer. The landscape different epigenetic signatures can vary considerably from one cancer type another, even ethnic group another case same This chapter discusses emerging role research. It about forms mechanisms their respective carcinogenesis light